For men battling advanced prostate cancer, Enzalutamide has become a game-changing treatment. Prescribed for cases that progress despite hormone therapy, it has helped thousands live longer with a better quality of life. However, with medical breakthroughs often come steep prices, and Enzalutamide is no exception.
In this 2025 cost guide, we’ll explore everything you need to know about Enzalutamide 160 mg, including how to lower costs through insurance, patient assistance programs, and alternatives such as generics or international access. Whether you're newly prescribed or planning for long-term use, this guide aims to help you navigate the complex world of drug pricing while ensuring continued access to vital prostate cancer medicines.
What Is Enzalutamide and Why Is It Prescribed?
Enzalutamide is an oral, hormone-based treatment that blocks androgen receptors, preventing male hormones like testosterone from fueling prostate cancer growth. It’s typically used in:
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Metastatic castration-resistant prostate cancer (mCRPC)
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Non-metastatic castration-resistant prostate cancer (nmCRPC)
The usual dosage is Enzalutamide 160 mg once daily, which is taken in capsule or tablet form. Whether it's branded as Xtandi or sourced as a generic in international markets, the therapeutic intent remains the same—to delay progression and enhance survival outcomes.
What Is the Enzalutamide Price in 2025?
One of the biggest challenges for patients and caregivers is understanding the enzalutamide price, especially in the U.S. Healthcare market.
Retail Pricing
In 2025, a one-month supply of enzalutamide tablets 160 mg can cost between $14,000 and $15,000 if purchased without any insurance or discount programs. That’s nearly $500 per tablet. This price tag can be daunting, particularly for long-term treatment regimens.
These numbers, however, reflect the sticker price. Real-world costs can be much lower with the right resources.
Insurance Coverage for Enzalutamide
1. Private Insurance
Most commercial insurance plans cover Enzalutamide for FDA-approved uses. However, co-pays and coinsurance may still be high depending on the plan. It’s common for patients to face costs ranging from a few hundred to several thousand dollars monthly unless they’ve met their annual out-of-pocket maximums.
2. Medicare
If you’re on Medicare Part D, Enzalutamide is likely included in your plan’s formulary. However, like with private insurance, co-insurance rates can leave patients paying thousands per year. In 2025, a policy change caps Medicare prescription costs at $2,000 annually, which is a huge win for cancer patients on expensive therapies.
3. Medicaid
Medicaid beneficiaries in most states will find that enzalutamide capsules are covered, though prior authorization is generally required. Co-pays are usually minimal or zero, making Medicaid one of the most cost-effective ways to access this treatment.
Assistance Programs for Lowering Costs
Many patients qualify for financial support, regardless of their insurance status. Here are some of the best options in 2025:
1. Manufacturer Programs
The drug’s manufacturer offers a Patient Assistance Program (PAP) for uninsured or underinsured patients. Depending on income level, this program may cover the entire cost of the medication.
Additionally, co-pay cards are available for those with commercial insurance, potentially reducing your cost to as little as $0 per month. These cards do not apply to government insurance plans like Medicare or Medicaid.
2. Nonprofit & Foundation Help
Organizations such as:
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CancerCare
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The Assistance Fund
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HealthWell Foundation
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Patient Access Network (PAN) Foundation
offer grants to help cover out-of-pocket costs, transportation, and even other supportive medications required alongside Enzalutamide.
Is There a Generic Enzalutamide in 2025?
While still under patent protection in the U.S., Enzalutamide Generic Price is significantly lower in countries where generics have been approved, like India. These generics are manufactured under stringent quality standards by companies such as Glenmark, BDR Pharma, and Cipla.
Although not yet FDA-approved for U.S. sale, generic versions are legally available through licensed international wholesale pharmacies, often with a valid prescription. A one-month supply of generic Enzalutamide can cost between $200 and $400, compared to $14,000+ for the branded version in the U.S.
For patients considering this option, it’s important to verify the source and ensure the medication comes from a regulated and certified pharmaceutical exporter.
How to Save on Enzalutamide in 2025
Here are practical strategies that can significantly lower your medication costs:
1. Use Prior Authorization Support
If your plan requires prior authorization, your healthcare provider can help submit necessary documentation to justify medical need. Don't delay treatment while waiting—start the process early.
2. Enroll in Manufacturer or Nonprofit Programs
Even if you believe you won’t qualify, apply! Many patients are surprised to discover they meet income or insurance criteria for assistance.
3. Consider International Pharmacy Options
Importing enzalutamide tablets 160 mg from international suppliers can dramatically reduce your costs. Reputable companies specialize in exporting prostate cancer medicines to over 150 countries, offering both branded and generic forms at wholesale prices.
4. Use Drug Discount Cards
Platforms like GoodRx, SingleCare, or OddwayInternational may offer limited discounts on Enzalutamide, especially when filled through participating pharmacies. While savings are modest, they can be helpful for one-time purchases or bridging gaps in coverage.
5. Watch for Generic Launches
The patent expiration for Enzalutamide is expected soon. Once generics are FDA-approved in the U.S., the Enzalutamide Generic Price is anticipated to drop by 70% or more. This could redefine access for thousands of patients overnight.
Real-World Case Example
Let’s say you’re a 67-year-old on Medicare Part D, prescribed enzalutamide capsules for mCRPC. Your annual retail cost would be close to $180,000 without insurance.
But here’s how you could save:
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With Medicare’s new $2,000 annual cap (as of 2025), your maximum cost is automatically limited.
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You apply for supplemental help through HealthWell Foundation and receive a $1,000 travel grant and $2,500 in additional support.
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You work with an international pharmacy and source generic Enzalutamide at $350/month for bridge therapy until insurance starts.
End result? You maintain continuity of care while saving tens of thousands annually.
Understanding the Future of Enzalutamide Access
2025 is a pivotal year for prostate cancer treatment pricing. With new caps on out-of-pocket costs for Medicare patients and the global rise of enzalutamide generic price options, more patients than ever can afford long-term therapy. But the journey still requires awareness, planning, and advocacy.
Conclusion: Planning Ahead to Afford Enzalutamide
The journey through cancer treatment is challenging enough—financial stress shouldn’t be part of it. Whether you're insured, uninsured, or somewhere in between, there are more resources than ever to help make Enzalutamide 160 mg affordable in 2025.
By understanding your coverage, applying for assistance programs, comparing global prices, and keeping an eye out for FDA-approved generics, you can secure access to life-saving treatment without breaking the bank.
And remember: enzalutamide capsules are more than just medicine—they represent time, strength, and a chance for a longer, fuller life.
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